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The Water Cooler
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Any of you been taking acetaminophin long term?
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<blockquote data-quote="nemesis" data-source="post: 2360894" data-attributes="member: 12082"><p>It's for a condition called "idiopathic neuropathy." I'd been suffering the symptoms for several months before I finally went to my doc. I also consulted two additional specialists. I've since had blood tests, x-rays and MRIs.</p><p></p><p>"Idiopathic" mostly means they don't know why I got it. I started drinking alcohol maybe two or three years ago and sometimes neuropathy happens from long term alcohol abuse. I didn't fall in that category but, regardless, I quit drinking. </p><p></p><p>The best they can do is treat the symptoms since they don't know what caused it. The acetaminophen is in a pill that also contains hydrocodone. 325 mg of acetaminophen. My primary care provider just cautions me to keep the acetaminophen dosage to no more than 2 grams a day. He cautions that for chronic usage. Definitely no more than 3 grams/day.</p><p></p><p>Badge Bunny, I'm really sorry you're having such a hard time with your condition. Speaking of 4 grams, doing the math, etc. Try calculating the max dose ceiling at any given time by computing the half life, etc. Especially since they don't know <em>exactly</em> what the half life is. I've seen estimates everywhere from 1 hour to 4 hours. I mostly see 1 to 2 1/2 hours. I've arbitrarily chosen 2 hours.</p><p></p><p>So, figure two extra strength Tylenol = 1000 mg = 1 gram. Half life = 2 hours. In two hours, that's 500 mg. In another 2 hours, that's 250 mg. In another 2 hours, that's 125 mg. So after the initial dose of 1000 mg (which is the maximum recommended allowable dose at any one time, for safety's sake), 6 hours later our (hypothetical) patient still has 125 mg in his system. But his therapy calls for 2 tablets every six hours. He takes two more. He's already got 125 mg in his system, he takes 1000 mg more, now he's got 1125 mg in his system which is 125 mg over the recommended limit. </p><p></p><p>It gets really confusing. Not only should one not go over 4 grams/day, he should be careful to space the doses apart so as not to violate the above. </p><p></p><p>In addition to staying well under 4 grams/day, I'm also trying to ingest foods that help improve liver function. Green tea. Walnuts. Leafy veges. That might just be so much voodoo, but what's the harm? (Of drinking green tea?) </p><p></p><p>Best of luck to you.</p></blockquote><p></p>
[QUOTE="nemesis, post: 2360894, member: 12082"] It's for a condition called "idiopathic neuropathy." I'd been suffering the symptoms for several months before I finally went to my doc. I also consulted two additional specialists. I've since had blood tests, x-rays and MRIs. "Idiopathic" mostly means they don't know why I got it. I started drinking alcohol maybe two or three years ago and sometimes neuropathy happens from long term alcohol abuse. I didn't fall in that category but, regardless, I quit drinking. The best they can do is treat the symptoms since they don't know what caused it. The acetaminophen is in a pill that also contains hydrocodone. 325 mg of acetaminophen. My primary care provider just cautions me to keep the acetaminophen dosage to no more than 2 grams a day. He cautions that for chronic usage. Definitely no more than 3 grams/day. Badge Bunny, I'm really sorry you're having such a hard time with your condition. Speaking of 4 grams, doing the math, etc. Try calculating the max dose ceiling at any given time by computing the half life, etc. Especially since they don't know [I]exactly[/I] what the half life is. I've seen estimates everywhere from 1 hour to 4 hours. I mostly see 1 to 2 1/2 hours. I've arbitrarily chosen 2 hours. So, figure two extra strength Tylenol = 1000 mg = 1 gram. Half life = 2 hours. In two hours, that's 500 mg. In another 2 hours, that's 250 mg. In another 2 hours, that's 125 mg. So after the initial dose of 1000 mg (which is the maximum recommended allowable dose at any one time, for safety's sake), 6 hours later our (hypothetical) patient still has 125 mg in his system. But his therapy calls for 2 tablets every six hours. He takes two more. He's already got 125 mg in his system, he takes 1000 mg more, now he's got 1125 mg in his system which is 125 mg over the recommended limit. It gets really confusing. Not only should one not go over 4 grams/day, he should be careful to space the doses apart so as not to violate the above. In addition to staying well under 4 grams/day, I'm also trying to ingest foods that help improve liver function. Green tea. Walnuts. Leafy veges. That might just be so much voodoo, but what's the harm? (Of drinking green tea?) Best of luck to you. [/QUOTE]
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