I wish nukes were the answer. It would be so easy to drop a dozen or so on the entire region and make pretty glass marbles out of them.
Unfortunately, the stakes with nukes are too high. The risk is too great. All it takes is one nuke-owning nation to think that we are targeting them, or getting to close and we end up with a nuke landing on our own soil, and that triggers more nukes.
I think we need to go back to Atomic bombs like Fat Man for this job. Our current Thermonuclear weapons are just too large to be of any use.
When making war, nothing should be off the table, including nukes, and no country should feel safe from our military, esp Russia, China, Pakistan, Iran, Saudi, Jordan. Support our enemy in any way and your country becomes the enemy and will be targeted.