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The Water Cooler
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<blockquote data-quote="tRidiot" data-source="post: 2503090" data-attributes="member: 9374"><p>Prevailing thought in the scientific community is that the venom attacks the lipids that make up cellular membranes... in exactly what way this happens is up to some debate and new research is shedding light, but the bottom line is, we don't have any way to effectively treat it.</p><p></p><p>The electrical shock therapy I have seen used, with good result. However, keep this in mind. The theory of electric shock treatment is to use the electrical current to denature (essentially unravel or deform) the proteins in the venom, thereby rendering them less- or ineffective. This must be done early, and with enough voltage to successfully attack the proteinaceous venom. However... while there are many anecdotal stories of this treatment working, keep in mind that the vast vast majority of fiddleback bites are essentially benign. The big rotten holes that some people develop are actually probably more related to an immune-mediated response of one's own body attacking tissue that has been affected by the venom already... so...</p><p></p><p>When you have a neighbor who tells you he keeps a loaded .45 by his bed and has never had a burglar come in, therefore they must be afraid of his .45, it may well be the same scenario. Burglars don't know a damn thing about his .45, but they have thus far happened not to pick his house... treating every fiddleback bite with a electrical shock therapy (from a taser, usually) may very well still result in the same number of bad outcomes as we have now. The fact remains that most fiddleback bites DON'T result in significant injury... so any home remedy used in anecdotal reports simply can't prove its effectiveness outside large-scale, controlled studies... and which of ya'll is gonna volunteer for that one???</p></blockquote><p></p>
[QUOTE="tRidiot, post: 2503090, member: 9374"] Prevailing thought in the scientific community is that the venom attacks the lipids that make up cellular membranes... in exactly what way this happens is up to some debate and new research is shedding light, but the bottom line is, we don't have any way to effectively treat it. The electrical shock therapy I have seen used, with good result. However, keep this in mind. The theory of electric shock treatment is to use the electrical current to denature (essentially unravel or deform) the proteins in the venom, thereby rendering them less- or ineffective. This must be done early, and with enough voltage to successfully attack the proteinaceous venom. However... while there are many anecdotal stories of this treatment working, keep in mind that the vast vast majority of fiddleback bites are essentially benign. The big rotten holes that some people develop are actually probably more related to an immune-mediated response of one's own body attacking tissue that has been affected by the venom already... so... When you have a neighbor who tells you he keeps a loaded .45 by his bed and has never had a burglar come in, therefore they must be afraid of his .45, it may well be the same scenario. Burglars don't know a damn thing about his .45, but they have thus far happened not to pick his house... treating every fiddleback bite with a electrical shock therapy (from a taser, usually) may very well still result in the same number of bad outcomes as we have now. The fact remains that most fiddleback bites DON'T result in significant injury... so any home remedy used in anecdotal reports simply can't prove its effectiveness outside large-scale, controlled studies... and which of ya'll is gonna volunteer for that one??? [/QUOTE]
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