My Redhawk came with pachmayer grips, and it hurt to shoot it. I replaced them with a stock set of rosewood grips and it became comfortable.
My Super Redhawk has hogue grips, and it is a pleasure to shoot, even with 300 grain CorBon solids.
The Hogue pistol grips and forends for shotguns are much friendlier than any of several others I have used, and the overmolded rifle stocks are my first choice for anything short of benchrest shooting. CB