I vote for a Ruger GP 100. Target practice with 38's and load with 357's for real action. They are a bit heavy, but there is nothing to go wrong with this revolver.
N frame smith in 357. best all around gun by far. you could load light enough for small game or heavy enough for deer or even elk size game. i'm thinkin the SHTF gun. if the end came today thats what id grab.
If I could find (& afford) a nickeled 6" Python.....otherwise my 17yr old GP100SS 4" fixed.....'course, a 6" SS GP would also do nicely. No hull spitters for me, thanx.