Absolutely not. In fact, TSA and the airlines recommend against it. It will allow any TSA agent to access your case which they are not allowed to do. You use a keyed lock and maintain possesion of that key and don't give it to anyone...that's the rules. If an airline agent or TSA agent needs to check it for inspection or verification it's unloaded, they will have you open it and then relock it. I travel with weapons quite a bit.For those that have traveled with their firearms, did you use a TSA approved lock or go with your own? I want to make sure my rifle is secure, but my guess is that a bad guy will easily have the master TSA approved lock key.
Check with the airline you're using, they will tell you. I'll add that American is the most gun-friendly carrier I've dealt with.
Most weapons stolen from airports have used TSA locks and cases using only one lock.