If it's something you really want to do, I'd say 'go for it.' HOWEVER, whatever waters you are going to fish, you need to know like the back of your hand. You should be able to consistently get onto fish wherever you take your clients. If you can't, you're not gonna' last very long. Guides get a LOT of repeat clients, if they are good, and those references mean a ton if you are going to build a business. What they say is true ... it only takes one "Oh, crap!" to wipe out all the "attaboys!"